STrengthening the REporting of Immunogenomic Studies
The 'Strengthening the Reporting of Observational Studies in Epidemiology' (STROBE) and 'Strengthening the Reporting of Genetic Association studies' (STREGA) statements enumerate guidelines for improving the interpretation of genetic studies, particularly genome-wide association studies (GWAS) and meta-analyses, as well as gene-based population and evolutionary studies.

The STrengthening the REporting of Immunogenomic Studies (STREIS) statement extends the STREGA statement for reporting studies of the germline immunogenome (HLA and KIR gene systems, and other complex immune-related gene systems), and addresses specific challenges to performing genetic studies using immunogenomic data.

STREIS provides guidance for addressing the extensive polymorphism associated with immunogenomic loci, the variety of genotyping systems in use, the complexities of transplantation studies, and the unique role played by the MHC and LRC regions in predisposition to disease (in both the strength and complexity of associations), and the complex nomenclatures used to describe these genes in genetic studies.

Read the STREIS statement (or download it here).

Download the STREIS Checklist.

Commentaries on STREIS can be found in the following journals:
Human Immunology
International Journal of Immunogenetics

The STREIS statement has been cited by the following: