UPDATE NOMENCLATURE

Toward this end, we have developed Update NomenCLature (UNCL), which will translate non-colon-delimited HLA allele names (e.g., A*01010101) to their colon-delimited counterparts (e.g., A*01:01:01:01), and will update allele names that have changed as the result of a nomenclature change (i.e., DPB1*0502 will be translated to DPB1*104:01, and HLA-C allele prefixes will be changed from Cw* to C*).

In addition to translating whole allele names, UNCL can translate allele-names that have been truncated to two, four, or six digits (e.g., A*01, A*0101, or A*010101) to their colon-delimited counterparts truncated to the appropriate number of polymorphic domains (e.g., A*01, A*01:01, or A*01:01:01).

UNCL uses the translation source table available at http://hla.alleles.org/data/txt/Nomenclature_2009.txt to perform translations; this file can also be obtained via FTP from ftp://ftp.ebi.ac.uk/pub/databases/imgt/mhc/hla/.

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System Requirements
UNCL is a web-based implementation of a script written in the R statistical computing environment and requires only an internet connection and a modern javascript-enabled web-browser (e.g., Internet Explorer 8, Firefox 3, or Safari 4).